HUMAN EMBRYONIC LUNG FIBROBLAST DIPLOID CELL STRAIN SUITABLE FOR THE PRODUCTION OF VIRUS AND PROCESS FOR THE PRODUCTION OF VARICELLA ZOSTER VIRUS USING SAME

摘要

A human embryonic lung fibroblast diploid cell strain LBHEL (KCTC 0127BP) is hig hly susceptible to varicella zoster virus (VZV). a cell-free varicella zoster virus (VZV) is produced by (a) culturing the human embryonic lung fibroblast diploid cell strain LBHEL (KCTC 0127BP) of claim 1 in a culture vessel to give cultured LBHEL cells; (b) i nfecting the cultured LBHEL cells with VZV to give VZV-infected cells; (c) culturing and harvesting the VZV-infected cells; (d) dis rupting the harvested cells to obtain a cell homogenate; and (e) centrifuging the cell homogenate to obtain a supernatant containing the cell -free VZV.