发明名称 CLONING AND EXPRESSION OF BIOLOGICALLY ACTIVE ALPHA-GALACTOSIDASE A.
摘要 The invention discloses a method for producing secreted proteins, comprising the steps of (a) culturing a transformed mammalian cell containing a nucleotide sequence encoding the secreted protein operatively associated with a nucleotide sequence that regulates gene expression; and (b) isolating said protein from the mammalian cell culture. <IMAGE>
申请公布号 EP0670896(A4) 申请公布日期 1997.08.20
申请号 EP19940902448 申请日期 1993.11.30
申请人 THE MOUNT SINAI SCHOOL OF MEDICINE, OF THE CITY UNIVERSITY OF NEW YORK 发明人 DESNICK, ROBERT J.;BISHOP, DAVID F.;IOANNOU, YIANNIS A.
分类号 C12N15/09;A61K35/18;A61K38/00;C07K14/31;C12N9/10;C12N9/24;C12N9/40;C12N15/54;C12N15/56;C12R1/91;(IPC1-7):C12N15/00 主分类号 C12N15/09
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