发明名称 |
NON-NUCLEOTIDE LINKING REAGENTS FOR NUCLEOTIDE PROBES |
摘要 |
A versatile reagent with a non-nucleotide monomeric unit having a ligand, and first and second coupling groups which are linked to the non-nucleotide monomeric unit. The ligand can be either a functional moiety, such as a label or intercalator, or a linking arm which can be linked to such a moiety. Such reagent permits preparation of versatile nucleotide/non-nucleotide polymers, having any desired sequence of nucleotide and non-nucleotide monomeric units, each of the latter of which bear a desired ligand. These polymers can for example, be used as probes which can exhibit enhanced sensitivity and/or which are capable of detecting a genus of nucleotides each species of which has a common target nucleotide sequence of interest bridged by different sequences not of interest.
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申请公布号 |
CA1339303(C) |
申请公布日期 |
1997.08.19 |
申请号 |
CA19880577911 |
申请日期 |
1988.09.20 |
申请人 |
GEN-PROBE INCORPORATED |
发明人 |
ARNOLD, LYLE JOHN JR.;REYNOLDS, MARK ALAN;BHATT, RAM SAROOP |
分类号 |
G01N33/58;C07F9/14;C07F9/146;C07F9/24;C07H21/00;C07H21/02;C07H21/04;C12Q1/68;(IPC1-7):C07F9/06;C07F9/28 |
主分类号 |
G01N33/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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