发明名称 MENEKIKIOKUSAIBOKENDAKUEKIOYOBISONOCHOSEIHOHO
摘要 A method of preparing an immunity memory cell suspension, wherein cells consisting of T-cells are separated from cells collected from an immunity sensitized individual immunized against a particular pathogen and are mixed with an antibody reactive to a histocompatibility antigen specific to a prescribed species of cells for producing antigen-antibody complexes by the antibody and those of the separated cells which have the histocompatibility antigen, whereupon a blood serum is added to the cells containing the antigen-antibody complexes for causing the complement in the blood serum to bind to the antigen-antibody complexes and thereby destroying the cells having the histocompatibility antigen and allowing the remaining cells to persist. To these persisting cells is then added an antibody reactive to a histocompatibility antigen specific to immunity memory cells and from the resultant cells are separated the immunity memory cells which have the histocompatibility antigen specific to immunity memory cells. Immunity memory cells may be cultured and subcultured successively through a plurality of generations to establish a continuous line of cells which originates in the immunity memory cells thus separated from the initial immunity sensitized individual.
申请公布号 JP2639834(B2) 申请公布日期 1997.08.13
申请号 JP19880300726 申请日期 1988.11.30
申请人 JIO RISAACHI JUGEN 发明人 DOI MITSURU
分类号 C12N5/00;A61K35/12;A61K35/14;A61K39/395;A61P31/12;A61P35/00;C12N5/02;C12N5/0783 主分类号 C12N5/00
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