发明名称 |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
摘要 |
This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
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申请公布号 |
US5656643(A) |
申请公布日期 |
1997.08.12 |
申请号 |
US19950385258 |
申请日期 |
1995.02.08 |
申请人 |
RHONE-POULENC RORER PHARMACEUTICALS INC. |
发明人 |
SPADA, ALFRED P.;MAGUIRE, MARTIN P.;PERSONS, PAUL E.;MYERS, MICHAEL R. |
分类号 |
A61K31/4375;A61K31/47;A61K31/4709;A61K31/4725;A61K31/498;A61K31/517;C07D213/64;C07D215/20;C07D401/04;C07D409/04;(IPC1-7):A61K31/47;C07D401/06;C07D401/12 |
主分类号 |
A61K31/4375 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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