发明名称 Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
摘要 This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
申请公布号 US5656643(A) 申请公布日期 1997.08.12
申请号 US19950385258 申请日期 1995.02.08
申请人 RHONE-POULENC RORER PHARMACEUTICALS INC. 发明人 SPADA, ALFRED P.;MAGUIRE, MARTIN P.;PERSONS, PAUL E.;MYERS, MICHAEL R.
分类号 A61K31/4375;A61K31/47;A61K31/4709;A61K31/4725;A61K31/498;A61K31/517;C07D213/64;C07D215/20;C07D401/04;C07D409/04;(IPC1-7):A61K31/47;C07D401/06;C07D401/12 主分类号 A61K31/4375
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