发明名称 ANTIULCER MEDICINE
摘要 PROBLEM TO BE SOLVED: To obtain an antiulcer medicine containing friedelan-3-β-ol or a β- sitosterol compound as an active ingredient, exhibiting an antiulcer action, especially exhibiting an improving effect on a hydrochloric acid ethanol gastric mucosa lesion in an acute gastric ulcer model, and free from a side effect. SOLUTION: This antiulcer medicine contains frledelan-3-β-ol of formula I or a compound of formula II (R is H, a group of formula III or a group of formula IV) (namely, β-sitosterol, β-sitosterol-3-0-6-palmitoyl-β-D-glucoside or β-sitosterol-3-0-β-D-glucoslde) as an active ingredient. The antiulcer medicine is prepared in the form of powder, granules, tablets, sugar-coated tablets, capsules, solutions, etc., and administered e.g. at a dose of 0.1-500 mg/kg body once to five times a day.
申请公布号 JPH09208598(A) 申请公布日期 1997.08.12
申请号 JP19960037482 申请日期 1996.01.31
申请人 NIPPON MEKTRON LTD 发明人 NAKAMURA MOTOYUKI;NAKASUMI TETSUO;YOSHIZAWA TOYOKICHI;MINAGAWA YUMIKO
分类号 A61K31/56;A61K31/575;A61K31/70;A61K36/18;A61P1/04;A61P25/04;A61P29/00;C07J63/00 主分类号 A61K31/56
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