| 摘要 |
PROBLEM TO BE SOLVED: To obtain a prophylactic or treating agent for virus diseases containing a compound having anti-endothelin activity. SOLUTION: This agent contains 0.01-100wt.% preferably 0.1-50wt.% of a cyclic hexapeptide expressed by the formula (X and Y are each a D-, L- or DL-isomer of anα-amino acid residue; A is a D-acidic-α-amino acid residue; B is a D- or L-neutral-α-amino acid residue; C is an L-α-amino acid residue; E is a D-α-amino acid residue having an aromatic ring), its ester, its salt, etc., as an active component. The agent is effective for a virus disease such as virus hepatitis, influenza, virus encephalitis, virus enteritis, virus myocarditis, virus pericarditis, etc. A daily dose is 10-1000mg for oral administration and 1-500mg for intravenous administration. |
