摘要 |
<p>Nucleoside analogues in which a group M replaces the natural base where M is (1) or (2) or (3), where each of X?1, X2 and X3¿ are C or N, each of R?6 and R7¿ is the same or different and each is H, NO¿2?, CO, COR?8, OR8¿, CN, O, CON(R8)2, COOR8, SO2R8, SO3R8, SR8, NHCHO, (CH¿2)n(R?8)2, halogen, or a reporter moiety, each of R?8 and R9¿ is H or hydrocarbyl or a reporter moiety, and n is 0-4. The analogues are substrates for polymerase and terminal transferase enzymes.</p> |