| 发明名称 |
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE |
| 摘要 |
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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| 申请公布号 |
CA2243507(A1) |
申请公布日期 |
1997.08.07 |
| 申请号 |
CA19972243507 |
申请日期 |
1997.01.27 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DINSMORE, CHRISTOPHER J.;HARTMAN, GEORGE D. |
| 分类号 |
A61K31/4164;(IPC1-7):C07D233/64;A61K31/41;A61K31/415;A61K31/435;A61K31/495;A61K31/535;A61K31/54;A61K31/55;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07D413/00;C07D417/00;C07D471/04;C07D495/04 |
主分类号 |
A61K31/4164 |
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