CHINOLINE AND BENZIMIDAZOLE DERIVATIVES AS BRADYKININ AGONISTS

摘要

This invention relates to a compound of formula (1) wherein R<1> is halogen, etc., R<2> is halogen, etc., R<3> is amino substituted with substituent(s) selected from the group consisting of lower alkyl and acyl, etc., R<4> is heterocyclic (lower)alkyl, R<5> is lower alkyl, and A<1> is lower alkylene, and pharmaceutically acceptable salts thereof, to processes for preparation thereof, to a pharmaceutical composition comprising the same, and to methods of using the same therapeutically in the prevention and/or the treatment of hypertension or the like.