发明名称 |
Fluorescent labels and their use in separations |
摘要 |
Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids.
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申请公布号 |
US5654419(A) |
申请公布日期 |
1997.08.05 |
申请号 |
US19940189924 |
申请日期 |
1994.02.01 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MATHIES, RICHARD A.;GLAZER, ALEXANDER;JU, JINGYUE |
分类号 |
G01N33/53;C12Q1/68;G01N33/533;G01N33/542;G01N33/566;G01N33/58;(IPC1-7):C07H21/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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