发明名称 Nye 2-cyano-3-hydroksy-propenamider og farmasöytiske preparater inneholdende slike
摘要 <p>The invention relates to the products <IMAGE> in which A, B and E represent =CH- or N with A or B or E = N, R represents cycloalkyl, alkenyl or alkynyl (>/= C6), R1 represents H or (C1-3)alkyl, R2 and R3 represent H, Hal, CN, NO2, (C1-6)alkyl, -cycloalkyl, -alkoxy or -alkylthio, -(CH2)m-CX3, -O-(CH2)m-CX3, -S-(CH2) m-CX3, -O-(CX2)m-CX3 or -S-(CX2)m-CX3, m being 0 to 3 and X being halogen, or -COR4, R4 being H, alkyl or cycloalkyl (>/= C3) or R2 and R3 together form -O-CH2-O-, as well as to their tautomeric forms and to their salts with bases. The products (I) have advantageous anti-inflammatory properties.</p>
申请公布号 NO300839(B1) 申请公布日期 1997.08.04
申请号 NO19940000020 申请日期 1994.01.04
申请人 ROUSSEL-UCLAF 发明人 KUO, ELIZABETH ANNE
分类号 A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/4425;A61P29/00;A61P35/00;C07D213/40;C07D213/75;C07D213/84;(IPC1-7):C07D213/74 主分类号 A61K31/44
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