发明名称 PYRROLOPYRIMIDINES AND PROCESSES FOR THEIR PREPARATION
摘要 There are described compounds of formula (I) wherein R1 and R2 are as defined in the description, Q is heterocyclyl bonded via a ring nitrogen atom and having formula (IA) wherein R3 and R4 and m and n are as defined in the description, the ring marked A is a heterocyclyl having from 5 to 9 ring atoms and having at least one saturated bond, it being possible for a further ring hetero atom selected from O and S to be present in addition to the bonding nitrogen atom, the ring system marked B is a free or benzo-, thieno-, furo-, pyrrolo- or dihydropyrrolo-fused carbocyclic ring having from 5 to 9 carbon atoms that is fused to the ring A and may be unsaturated, partially saturated or fully saturated, and the bond marked by a parallel dotted line between the ring systems marked A and B is either a single bond or a double bond, and a salt thereof where at least one salt-forming group is present. The compounds are inhibitors of protein kinases and have, for example, antitumour activity.
申请公布号 CA2242354(A1) 申请公布日期 1997.07.31
申请号 CA19972242354 申请日期 1997.01.13
申请人 NOVARTIS AG 发明人 BOLD, GUIDO;TRAXLER, PETER;FREI, JOERG
分类号 A61K31/00;A61K31/505;A61K31/519;A61K31/529;A61P17/00;A61P17/06;A61P35/00;A61P35/02;A61P43/00;C07D487/04;(IPC1-7):C07D487/04;C07D519/00;C07F7/10;A61K31/55;A61K31/695 主分类号 A61K31/00
代理机构 代理人
主权项
地址