Methods and compositions for treating hypertension, angina and other disorders using optically pure (-) amlodipine

摘要

A composition in the form of a tablet, cachet or capsule comprising an amount of (-) amlodipine or a pharmaceutically acceptable salt thereof, wherein the amlodipine present in the composition contains at least 90% by weight of (-) amlodipine and 10% by weight or less of (+)-amlodipine and wherein the composition is for the treatment of a human in need of antihypertensive therapy and the amount is sufficient to alleviate hypertension but insufficient to cause adverse side-effects associated with the administration of racemic amlodipine.