发明名称 |
ACYLATED INSULIN ANALOGS. |
摘要 |
<p>The present invention relates to the field of diabetes. More particularly, the invention relates to a monomeric insulin analog wherein the A chain is the naturally occurring sequence of the human insulin A chain and the B chain is modified at either position B28 and B29 or both. The analog is mono-acylated at the N-terminal of the A chain or B chain or at the lysine. The acylated insulin analogs have an extended duration of action.</p> |
申请公布号 |
MX9703508(A) |
申请公布日期 |
1997.07.31 |
申请号 |
MX19970003508 |
申请日期 |
1995.11.14 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
JEFFREY CLAYTON BAKER;JOSE MICHAEL HANQUIER |
分类号 |
C12N15/09;A61K38/00;A61K38/28;A61P3/08;A61P5/38;C07K14/62;G01N33/68;(IPC1-7):A61K38/28 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|