| 发明名称 |
THERAPEUTIC APPLICATIONS OF T-BAM (CD40-L) TECHNOLOGY TO TREAT INFLAMMATORY KIDNEY DISEASES______________________________________ |
| 摘要 |
Activation by CD40 ligand of renal cells bearing CD40 on the cell surface is inhibited, both in vivo and ex vivo, with an agent capable of inhibiting interaction between CD40 ligand and CD40 on the cells. Inflammatory kidney diseases are treated.
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| 申请公布号 |
CA2243531(A1) |
申请公布日期 |
1997.07.24 |
| 申请号 |
CA19972243531 |
申请日期 |
1997.01.16 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;BIOGEN, INCORPORATED;BIOGEN, INCORPORATED |
发明人 |
THOMAS, DAVID W.;KARPUSAS, MIHAIL N.;CHESS, LEONARD;YELLIN, MICHAEL J.;LEDERMAN, SETH |
| 分类号 |
G01N33/566;A61K31/00;A61K38/00;A61K39/395;A61K45/00;A61P13/00;A61P13/12;C07K14/705;C07K16/18;C07K16/28;C12N5/00;C12N15/02;C12P21/08;C12R1/91;G01N33/15;(IPC1-7):A61K39/395;C12N5/06;C12N5/08;A61K38/19;G01N33/554;G01N33/577 |
主分类号 |
G01N33/566 |
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