摘要 |
<p>Subsets of cells from hematopoietic and non-hematopoietic tissues are used for bone and cartilage regeneration. Bone and cartilage precursor cells are isolated from peripheral blood, bone marrow and adipose tissue using antibodies and other reagents that recognize hematopoietic cell surface marker CD34 and other markers on CD34+ cells. Precurosr cells may be used for in vivo bone or cartilage regeneration by transplanting the cells with or without a carrier material to sides in the body requiring bone or cartilage repair without the need for in vitro culturing. Precursor cells may also be used to seed prosthetic devices to enhance implantability.</p> |