摘要 |
Therapeutical compositions comprising from 0.1 to 20 % by weight of a cyclosporin and a vehicle comprising from 1 to 60 % by weight of polyethers constituted by, preferably, substances like ethoxy diglycol or polyethylene glycols 300 to 600 and/or substances like preferably dimethyl isosorbide, dimethyl isoidide and dimethyl isomannide, and from 1 to 60 % by weight of a mixture of glyceryl monoesters of C8-C22 fatty acids and hexaglyceryl to pentadecaglyceryl monoesters of C8-C22 fatty acids in a ratio of 1:2 to 1:6. The therapeutical compositions preferably additionally comprise further adjuvants like anti-oxidants, preserving agents and stabilisers, flavouring agents, thickening agents and diluents. The compositions for external use preferably additionally comprise lipoaminoacids.
|
申请人 |
GALENA A S;NORTON HEALTHCARE LTD.;STUCHLIK, MILAN;ANDRYSEK, TOMAS;JEGOROV, ALEXANDER;HUSEK, ALES;MATHA, VLADIMIR;STUCHLIK, JOSEF |
发明人 |
STUCHLIK, MILAN;ANDRYSEK, TOMAS;JEGOROV, ALEXANDER;HUSEK, ALES;MATHA, VLADIMIR;STUCHLIK, JOSEF |