发明名称 |
BACTERIAL DONOR CELL USEFUL IN CONJUGATION |
摘要 |
The present invention relates to a modified bacterial donor cell useful in conjugation, the cell containing i) a plasmid comprising a DNA construct encoding the polypeptide of interest, and at least one cis-acting DNA sequence required for the transfer of said plasmid by conjugation in the presence of a trans-acting mobilizing element, and ii) at least one DNA sequence encoding said trans-acting mobilizing element, wherein the donor cell has a reduced capacity, relative to a parent cell, of producing a bactericidal agent which kills or prevents growth in a population of recipient cells. |
申请公布号 |
WO9726361(A2) |
申请公布日期 |
1997.07.24 |
申请号 |
WO1997US00899 |
申请日期 |
1997.01.17 |
申请人 |
NOVO NORDISK BIOTECH, INC. |
发明人 |
SLOMA, ALAN, P.;WIDNER, WILLIAM, R. |
分类号 |
C12N15/09;C12N1/21;C12N9/54;C12N15/75;C12R1/07 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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