Isolated DNA encoding a protein or polypeptide having at least one biological activity of a vertebrate fringe protein, as well as the protein or polypeptide encoded thereby, are described. Assays for identifying agents which alter the expression of the described fringe genes and assays for agents which alter the production of angiogenic precursors, the formation of the apical ectodermal ridge and the subdivisions of the neural tube are also described.
申请公布号
WO9726276(A2)
申请公布日期
1997.07.24
申请号
WO1997US00849
申请日期
1997.01.15
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;LAUFER, EDWARD, M.;OROZCO, OLIVIA, E.;TABIN, CLIFFORD, J.
发明人
LAUFER, EDWARD, M.;OROZCO, OLIVIA, E.;TABIN, CLIFFORD, J.