发明名称 |
Lock and key micelles |
摘要 |
A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a "key" unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefrom, at least one of the branches including a shank portion extending therefrom having a terminal moiety at an end thereof for binding to a complimentary acceptor of a lock unimolecular micelle. Together, the lock and key micelles form a unit, either irreversibly or reversibly bound wherein the lock micelles is a soluble receptor engineered to specifically bind to the specifically engineered key micelle.
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申请公布号 |
US5650101(A) |
申请公布日期 |
1997.07.22 |
申请号 |
US19940280591 |
申请日期 |
1994.07.25 |
申请人 |
UNIVERSITY OF SOUTH FLORIDA |
发明人 |
NEWKOME, GEORGE R.;MOOREFIELD, CHARLES N.;BAKER, GREGORY R. |
分类号 |
A61K9/107;A61K47/30;A61K47/48;B01F17/30;C07C233/47;C07D213/68;C07D213/75;C07D239/62;C07D239/64;C08G73/02;C08G73/06;C08J3/02;(IPC1-7):A61K9/107;A61K9/50;B01J13/20;B01J13/22 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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