发明名称 |
Lanthionine antibiotic compositions and methods |
摘要 |
Certain bacteria indigenous to humans produce antimicrobial substances called bacteriocins which inhibit other bacteria, including members of their own species. Mutacins are a class of antibiotic substances made by Streptococcus mutans. Disclosed is the purification and biochemical characterization of a novel lanthionine-containing mutacin peptide from S. mutans. The purified peptide is pH- and temperature-stable and its amino acid composition indicates the presence of lanthionine and beta -methyllanthionine. Also provided are methods of making and using the purified polypeptide.
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申请公布号 |
US5650320(A) |
申请公布日期 |
1997.07.22 |
申请号 |
US19940230473 |
申请日期 |
1994.04.20 |
申请人 |
UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION |
发明人 |
CAUFIELD, PAGE W.;NOVAK, JAN |
分类号 |
C07K14/315;C12N1/15;C12N1/21;C12N15/52;C12N15/74;(IPC1-7):C12N1/21;C12N15/63;C07H21/04 |
主分类号 |
C07K14/315 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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