发明名称 |
Tie-2 ligand 2 |
摘要 |
The present invention provides for an isolated nucleic acid molecule encoding human TIE-2 ligand. In addition, the invention provides for a receptor body which specifically binds human TIE-2 ligand. The invention also provides an antibody which specifically binds human TIE-2 ligand. The invention further provides for therapeutic compositions as well as a method of blocking blood vessel growth, a method of promoting neovascularization and a method of promoting the growth or differentiation of a cell expressing the TIE-2 receptor.
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申请公布号 |
US5650490(A) |
申请公布日期 |
1997.07.22 |
申请号 |
US19950373579 |
申请日期 |
1995.01.17 |
申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
DAVIS, SAMUEL;JONES, PAMELA F.;YANCOPOULOS, GEORGE D. |
分类号 |
A61K38/00;C07K14/515;(IPC1-7):A61K38/18;C07K14/475 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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