发明名称 |
Gene control |
摘要 |
The present invention relates to a recombinant genetic material which can be operably linked to protein encoding sequence comprising an expression control sequence having at least one promoter region and at least one repressor region such that basal expression in a tissue where the protein is required to be expressed is reduced whilst allowing induction of expression of the protein encoding sequence. Suitably the promoter is a p450 type promoter whilst suitably it is the p450 CYP1A1 promoter of the rat. The invention further provides a method of manufacturing proteins for polypeptides in the method of manufacturing or recombinant construct for transgene induction. |
申请公布号 |
AU1202297(A) |
申请公布日期 |
1997.07.17 |
申请号 |
AU19970012022 |
申请日期 |
1996.12.23 |
申请人 |
THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE;ROSLIN INSTITUTE (EDINBURGH) |
发明人 |
ANTHONY JOHN CLARK;CHARLES ROLAND WOLF |
分类号 |
A01K67/027;C12N9/02;C12N15/53;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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