| 发明名称 |
HEXACYCLIC CAMPTOTHECIN ANALOGUES, AND PROCESS FOR PREPARING THEM |
| 摘要 |
The present invention relates to novel hexacyclic camptothecin analogues, having a five-membered aza-heterocycle fused to ring (A) of camptothecin at positions 9 and 10. Such compounds possess high antitumor activity by inhibition of topoisomerase (I).
|
| 申请公布号 |
WO9725332(A1) |
申请公布日期 |
1997.07.17 |
| 申请号 |
WO1996EP05752 |
申请日期 |
1996.12.17 |
| 申请人 |
PHARMACIA & UPJOHN S.P.A.;BEDESCHI, ANGELO;CANDIANI, ILARIA;ZARINI, FRANCO |
发明人 |
BEDESCHI, ANGELO;CANDIANI, ILARIA;ZARINI, FRANCO |
| 分类号 |
A61K31/435;A61P35/00;C07D491/22;C07D498/22;C07D513/22;(IPC1-7):C07D491/22 |
主分类号 |
A61K31/435 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
