HUMAN G-PROTEIN COUPLED RECEPTOR

摘要

Human ATP receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the under-expression and over-expression of the ATP receptor polypeptides. Also disclosed are diagnostic methods for detecting a mutation in the ATP receptor nucleic acid sequences and detecting a level of the soluble form of the receptors in a sample derived from a host.