发明名称 |
Alpha-1-acid glycoprotein transgenic mice |
摘要 |
The mice of this invention heritably carry alpha-1-acid glycoprotein (AGP) genes which may be introduced by the transgenic methodology. These animal models are useful for various purposes including 1) assessment of the in vivo role of AGP in the clearance of individual drugs; 2) assessment of the influence of AGP on the pharmacological activity of individual drugs; 3) testing of hypotheses concerning the function of AGP; and 4) identification of the AGP gene cis-acting regulatory features.
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申请公布号 |
US5648597(A) |
申请公布日期 |
1997.07.15 |
申请号 |
US19900511470 |
申请日期 |
1990.04.20 |
申请人 |
UNIVERSITY OF SOUTH CAROLINA;HEALTH RESEARCH, INC. |
发明人 |
DEWEY, MICHAEL J.;BAUMANN, HEINZ;BERGER FRANKLIN G |
分类号 |
A01K67/027;C07K14/47;C12N15/12;C12N15/85;(IPC1-7):C12N5/00;C12N15/00 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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