| 摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing a specific L- carnitine compound and a polyunsaturated fatty acid and useful for the prevention and treatment of cardiovascular disorder, atherosclerosis, peripheral vascular disorder, anaphylactic shock and septic shock. SOLUTION: This composition contains an excipient and (A) L-carnitine or an alkanoyl-L-carnitine having a 2-8C (branched)alkanoyl, especially a 2-6C (branched)alkanoyl as the alkanoyl group [e.g., acetyl, propionyl, butyryl or (iso)valeryl] or its salt, (B) an (ω-3 polyunsaturated fatty acid (ester), a natural substance containing the acid or its extract [e.g., ethyl eicosapentaenoate, ethyl docosahexaenoate or fish oil (extract)] and optionally further (C) beeswax, behenolic acid or other polyunsaturated fatty acid existing in a natural substance such as seed corn oil. |
