| 摘要 |
PROBLEM TO BE SOLVED: To provide a composition for topical application, containing a specific flavanone mixture and an excipient, effective for promoting the differentiation of keratinocyte to keep the skin in fresh state and useful for decreasing the wrinkles, imparting the skin with moistness and treating light-damaged skin, etc. SOLUTION: This composition contains (A) 0.001-5.0% flavanone consisting of eriodictyol, taxifolin or their mixture, (B) 0.001-5.0% flavanone consisting of hesperetin, naringenin or their mixture, (C) an excipient for the components A and B and, as necessary, (D) a ceramide selected from a short-chain ceramide, pseudoceramide and neoceramide. The weight/mol ratio of B/A in the composition is 1:5 to 5:1 and the amount of the component D in the composition is 0.001-50%. |
