LOCALIZED INTRAVASCULAR DELIVERY OF GROWTH FACTORS FOR PROMOTION OF ANGIOGENESIS

摘要

Angiogenesis in cardiac and other tissues is promoted by the transmural delivery of angiogenic factors such as VEGF, FGF, EGF and PDGF, through blood vessels and other body lumens into the surrounding tissue. Usually, the angiogenic factor is delivered using a catheter (110) having infusion parts at its distal end. Optionally, the distal end of the catheter (128) is radially expanded to engage the infusion parts directly against the blood vessel wall.