PROCESS FOR PRODUCING BIOLOGICALLY ACTIVE FUSED PROTEINS
摘要
A process for producing biologically active fused proteins whereby novel biologically active fused proteins usable as a remedy or a diagnostic drug or applicable to gene therapy can be efficiently produced by appropriately selecting the optimum linker polypeptide. This process comprises incubating transformants obtained by the transformation by expression vectors which contain the DNA sequences encoding the amino acid sequences of proteins represented by the following formula: A-X-B wherein A and B represent respectively the subunits of a dimer protein or biologically active proteins and may be the same; and X represents a linker polypeptide.
申请公布号
WO9723639(A1)
申请公布日期
1997.07.03
申请号
WO1996JP03742
申请日期
1996.12.20
申请人
TORAY INDUSTRIES, INC.;TORAY RESEARCH CENTER, INC.;NAKATANI, IZUMI;TOMURA, MICHIO;KANAI, SHOZO;FUJIWARA, HIROMI;AKIYAMA, HIDEO