| 发明名称 |
TRICYCLIC AMIDES USEFUL FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES |
| 摘要 |
Novel compounds, such as formulae (1.0), (4.0), (22.0), (27.0), (32.0) and (39.0) are disclosed. Also disclosed are methods for inhibiting the abnormal growth of cells, for inhibiting farnesyl protein transferase and for treating cancers using the novel compounds.
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| 申请公布号 |
WO9723478(A1) |
申请公布日期 |
1997.07.03 |
| 申请号 |
WO1996US19603 |
申请日期 |
1996.12.19 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
DOLL, RONALD, J.;KELLY, JOSEPH, M.;NJOROGE, F., GEORGE;MALLAMS, ALAN, K.;REMISZEWSKI, STACY, W.;TAVERAS, ARTHUR, G. |
| 分类号 |
A61K31/44;A61K31/4427;A61K31/445;A61K31/4545;A61K31/495;A61K31/496;A61P35/00;A61P43/00;C07D401/04;C07D401/12;C07D401/14;(IPC1-7):C07D401/04 |
主分类号 |
A61K31/44 |
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