发明名称 |
Substrate useful for separating modified oligonucleotides |
摘要 |
Disclosed is a substrate useful for separating unmodified and modified mononucleotides and oligonucleotides. The substrate includes at least 12% polymer in at least 50% (volume:volume) organic solvent, the organic solvent being a denaturing agent. This substrate is easily removable from the capillary using low pressure. Also provided is a method of separating unmodified and modified mononucleotides and oligonucleotides utilizing this substrate.
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申请公布号 |
US5643717(A) |
申请公布日期 |
1997.07.01 |
申请号 |
US19930032856 |
申请日期 |
1993.03.16 |
申请人 |
HYBRIDON, INC. |
发明人 |
COHEN, AHARON S.;VILENCHIK, MARIA |
分类号 |
B01J20/26;C07H1/06;C07H19/06;C07H19/16;C07H21/00;C08L1/00;C08L1/26;C08L29/04;C08L33/24;C08L33/26;C12N15/10;G01N27/447;(IPC1-7):C12Q1/68 |
主分类号 |
B01J20/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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