发明名称 BENZYLIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE.
摘要 The present invention relates to compounds of formula (I): (wherein X is an optionally substituted benzylimidazole group; Y is an oxygen or sulfur atom; Z is a 2,4-dioxothiazolidine-5-ilidenylmethyl, 2,4-dioxothiazo-lidine-5-ilmethyl, 2,4-dioxooxazolidine-5-ilmethyl, 3,5-dioxooxadiazolidine-2-ilmethyl or N-hydroxyureidomethyl group; R is hydrogen, alkyl, alkoxy, halogen, hydroxy, nitro, amino or aralkyl; and m is an integer from 1 to 5(; having valuable activity for the treatment of several dysfunctions and/or prophylaxis, including one or more of: hyperlipemia, hyperglycemia, obesity, diminished tolerance to glucose (TDG), insulin resistance and diabetic complications.
申请公布号 MX9602122(A) 申请公布日期 1997.06.28
申请号 MX19960002122 申请日期 1996.06.03
申请人 SANKYO COMPANY, LIMITED 发明人 TAKASHI FUJITA;KUNIO WADA;MINORU OGUCHI;HIROAKI YANAGISAWA;KOICHI FUJIMOTO;TOSHIHIKO FUJIWARA;HIROYOSHI HORIKOSHI;TAKAO YOSHIOKA
分类号 C07D417/10;A61K31/4184;A61K31/42;A61K31/4245;A61K31/425;A61K31/427;A61P3/10;C07D235/06;C07D235/12;C07D277/24;C07D403/12;C07D413/12;C07D417/12;(IPC1-7):C07D235/24;C07D263/44;C07D277/14 主分类号 C07D417/10
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