发明名称 |
PEPTIDE-BASED INHIBITORS OF HIV REPLICATION |
摘要 |
<p>Described herein are oligopeptides useful to inhibit HIV replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 5 mu m concentration, exhibits greater than 95 % inhibition of HIV replication, in a standard assay.</p> |
申请公布号 |
GR3022838(T3) |
申请公布日期 |
1997.06.30 |
申请号 |
GR19970400513T |
申请日期 |
1997.03.17 |
申请人 |
ALLELIX BIOPHARMACEUTICALS INC. |
发明人 |
SUMNER-SMITH, MARTIN;BARNETT, RICHARD W.;REID, LORNE, S.;SONENBERG, NAHUM |
分类号 |
A61K38/00;A61K38/08;A61P31/12;C07K7/06;C07K7/08;C07K14/155;(IPC1-7):C07K7/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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