发明名称 |
Reversed phase chromatographic process |
摘要 |
A factory scale process for the reversed phase chromatographic decolorisation, separation and purification of water-soluble nonionic contrast media compounds from solutions containing nonionic compound impurities includes the steps of passing a solution through a decoloriser chromatographic column (2) and eluting the decoloriser column (2) with solvent. The packing in the decoloriser column (2) is regenerated by passing a regenerating solvent (20) through the packing, purifying the solvent (21) in a solvent recovery plant (25) and recycling the solvent. Waste solvent (33) produced on regenerating a purification column used in a recovery process may also be recovered in the solvent recovery plant (25). |
申请公布号 |
AU7707196(A) |
申请公布日期 |
1997.06.27 |
申请号 |
AU19960077071 |
申请日期 |
1996.12.02 |
申请人 |
MALLINCKRODT MEDICAL IMAGING-IRELAND |
发明人 |
ELIZABETH COLLINS;CONOR MURPHY;BRENDAN O'CALLAGHAN |
分类号 |
B01D15/08;C07C231/24;C07C237/46 |
主分类号 |
B01D15/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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