发明名称 RADIOLABELED GROWTH HORMONE SECRETAGOGUE
摘要 The present invention is directed to [<35>S]-N-[1(R)-[(1,2-dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperidin]-1'-yl)carbonyl]-2-(phenylmethyloxy)ethyl]-2-amino-2-methylpropanamide, and pharmaceutically acceptable salts thereof. This [<35>S] radioligand is useful in identifying and characterizing cellular receptors which play a role in the activity of growth hormone secretagogues. In addition, this [<35>S] radioligand is useful in assays which test compounds for growth hormone secretagogue activity.
申请公布号 WO9722367(A1) 申请公布日期 1997.06.26
申请号 WO1996US20007 申请日期 1996.12.16
申请人 MERCK & CO., INC.;DEAN, DENNIS, C.;MELILLO, DAVID, G.;NARGUND, RAVI;VAN DER PLOEG, LEONARDUS;PONG, SHENG-SHUNG;SCHAEFFER, JAMES, M.;SMITH, ROY, G. 发明人 DEAN, DENNIS, C.;MELILLO, DAVID, G.;NARGUND, RAVI;VAN DER PLOEG, LEONARDUS;PONG, SHENG-SHUNG;SCHAEFFER, JAMES, M.;SMITH, ROY, G.
分类号 A61K51/04;C07K5/06;(IPC1-7):A61K51/04;C07D487/10 主分类号 A61K51/04
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