发明名称 Modified VEGF oligonucleotides
摘要 Disclosed are oligonucleotides complementary to VEGF-specific nucleic acid useful in reducing the expression of VEGF. Also disclosed are pharmaceutical formulations containing such oligonucleotides useful for treating various disorders associated with neovascularization and angiogenesis.
申请公布号 US5641756(A) 申请公布日期 1997.06.24
申请号 US19950569926 申请日期 1995.12.08
申请人 HYBRIDON, INC. 发明人 ROBINSON, GREGORY S.
分类号 C12N15/09;A61K31/70;A61K31/7088;A61K38/00;A61K48/00;A61P3/08;A61P9/00;A61P9/10;A61P17/00;A61P27/02;A61P35/00;C07H21/02;C07H21/04;C12N5/02;C12N15/113;(IPC1-7):A61K31/70;C07H21/00;C12N5/10;C12Q1/68 主分类号 C12N15/09
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