发明名称 Thiol derivatives with metallopeptidase inhibitory activity
摘要 PCT No. PCT/EP96/05496 Sec. 371 Date Jun. 23, 1998 Sec. 102(e) Date Jun. 23, 1998 PCT Filed Dec. 9, 1996 PCT Pub. No. WO97/24341 PCT Pub. Date Jul. 10, 1997Compounds of formula (I) wherein R, R1, R2, R3 have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active ingredients are described. The compounds of formula (I) are endowed with a mixed ACE-inhibitory and NEP-inhibitory activity and are useful in the treatment of cardiovascular diseases.
申请公布号 ZA9610819(B) 申请公布日期 1997.06.24
申请号 ZA19960010819 申请日期 1996.12.20
申请人 ZAMBON GROUP S.P.A. 发明人 FRANCO PELLACINI;GABRIELE NORCINI;CLAUDIO SEMERARO;STEFANO ROMAGNANO;FRANCESCO SANTANGELO
分类号 C07D213/55;C07D277/30;C07D333/24 主分类号 C07D213/55
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