| 摘要 |
The present invention provides new methods, particularly computational methods, and compositions for the generation of nuclear receptor synthetic ligands based on the three-dimensional structure of nuclear receptors, particularly the thyroid receptor (herein referred to as "TR"). Also provided are crystals, nuclear receptor synthetic ligands, and related methods. |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SCANLAN, THOMAS, S.;BAXTER, JOHN, D.;FLETTERICK, ROBERT, J.;WAGNER, RICHARD, L.;KUSHNER, PETER, J.;APRILETTI, JAMES, L.;WEST, BRIAN, L.;SHIAU, ANDREW, K. |
