TOPICAL RETINOID COMPOSITION

摘要

Disclosed are topical retinol compositions and methods of applying such compositions to human skin. The topical compositions comprise (a) from about 1 % to about 60 % of a continuous silicone phase by weight of the composition, wherein the continuous silicone phase comprises from about 50 % to about 99.9 % organopolysiloxane and less than about 50 % by weight of a nonsilicone oil, by weight of the continuous silicone phase; (b) from about 30 % to about 90 % of an aqueous discontinuous phase by weight of the composition; (c) from about 0.0001 % to about 5 % retinoid by weight of the composition; and (d) from about 0.1 % to about 10 % of an emulsifier by weight of the composition. The topical compositions provide improved oxidative stability for retinoids incorporated in water-in-oil emulsions, and are preferably substantially free of conventional antioxidants.