| 发明名称 |
COMPLEMENTARY ADENOVIRAL VECTOR SYSTEMS AND CELL LINES |
| 摘要 |
The present invention provides multiply replication deficient adenoviral vectors having a spacer in at least one replication deficient adenoviral region, as well as complementing cell lines therefor. Also provided are means of constructing the multiply replication deficient adenoviral vectors and methods of use thereof, e.g., in gene therapy. |
| 申请公布号 |
WO9721826(A2) |
申请公布日期 |
1997.06.19 |
| 申请号 |
WO1996US19839 |
申请日期 |
1996.12.12 |
| 申请人 |
GENVEC, INC. |
发明人 |
KOVESDI, IMRE;BROUGH, DOUGLAS, E.;MCVEY, DUNCAN, L.;BRUDER, JOSEPH, T.;LIZONOVA, ALENA |
| 分类号 |
C12N15/09;A61K31/70;A61K35/76;A61K38/00;A61K48/00;A61P37/04;A61P43/00;C07K14/075;C07K14/47;C12N5/10;C12N7/00;C12N15/00;C12N15/12;C12N15/34;C12N15/86;C12N15/861;C12Q1/02;C12Q1/68;C12R1/92;G01N33/15 |
主分类号 |
C12N15/09 |
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