发明名称 |
Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin |
摘要 |
An overall process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing modified expandase enzyme. |
申请公布号 |
AU1097297(A) |
申请公布日期 |
1997.06.19 |
申请号 |
AU19970010972 |
申请日期 |
1996.11.27 |
申请人 |
GIST-BROCADES B.V.;UNIVERSITY OF OXFORD |
发明人 |
JOHN DAVID SUTHERLAND;ROELOF ARY LANS BOVENBERG;JAN METSKE VAN DER LAAN |
分类号 |
C12N1/21;C12N9/00;C12N9/02;C12N15/52;C12P35/00 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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