| 摘要 |
PROBLEM TO BE SOLVED: To selectively, efficiently and inexpensively provide a method for producing the subject compound useful as an intermediate for medicines and agrochemicals, capable of readily purifying by carrying out transalkylation reaction of brominated 4-cumenylphenol with an aromatic hydrocarbon. SOLUTION: (B) 2-Bromo-4-cumenylphenol or 2,6-dibromo-4-cumenylphenol obtained by brominating 4-cumenylphenol in the presence of (A) a Friedel-Crafts catalyst such as aluminum chloride or iron chloride is reacted with (C) an aromatic hydrocarbon such as (chloro)benzene, toluene, xylene, mesitylene, naphthalene, e.g. at 0-150 deg.C, especially 20-100 deg.C to carry out transalkylation to provide the objective 2-bromophenol or 2,6-dibromophenol. Furthermore, the components A and C are each preferably used in amounts of 0.1-2mol and 1-10mol based on 1mol component B. |
