发明名称 SOLID PHASE ORGANIC SYNTHESIS
摘要 A method of synthesis of a material corresponding to general formula R3 - X H, characterised in that it comprises a material corresponding to general formula (I), being cleaved as indicated enzymatically or non-enzymatically using acid catalysis in the presence of a nucleophile; wherein R1 represents a group providing the site for exo-enzyme or acid hydrolysis; R2 represents an optional intermediate linked to a solid support; R3 represents a residue of a carbohydrate, (oligo-)saccharide, (glyco-)peptide, (glyco-)lipid or of an organic molecule which is heterocyclic and/or aromatic; X represents O, N(H), N(R"), C(O)O, S, C(O)N(H) or C(O)N(R"), R" being a non-interfering substituent; and Support represents a solid support; is disclosed.
申请公布号 CA2239298(A1) 申请公布日期 1997.06.12
申请号 CA19962239298 申请日期 1996.12.06
申请人 GENZYME LIMITED 发明人 TURNER, NICHOLAS JOHN;FLITSCH, SABINE LAHJA
分类号 C07D249/18;C07B61/00;C07C323/25;C07C323/59;C07H1/00;C07K1/04;C07K9/00;(IPC1-7):C07K1/04;C12P21/02 主分类号 C07D249/18
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