发明名称 |
5-NAPHTHALEN-1-YL-1,3-DIOXANE DERIVATIVES, PREPARATION AND THERAPEUTICAL USE THEREOF |
摘要 |
<p>Compounds of general formula (I), wherein R1 is a hydrogen atom or a (C1-4) alkyl, (C3-6) cycloalkylméthyl or phenyl (C1-3) alkyl group optionally substituted on the phenyl ring by one or more atoms or groups selected from halogens and methyl, trifluoromethyl, methoxy and cyano groups, R2 is a hydroxy or alkoxy group or a group of general formula NR3R4 where each of R3 and R4 is a hydrogen atom, an alkyl group, a cycloalkyl group, a cycloalkylmethyl group, a phenyl group, a phenylmethyl group or a pyridinyl group, or R3 and R4, taken together with the nitrogen atom, form a pyrrolidine or piperidine ring, and n is 1, 2 or 3. The compounds are for therapeutical use.</p> |
申请公布号 |
WO9720836(A1) |
申请公布日期 |
1997.06.12 |
申请号 |
WO1996FR01926 |
申请日期 |
1996.12.04 |
申请人 |
SYNTHELABO;DARGAZANLI, GIHAD;EVANNO, YANNICK;FROST, JONATHAN;LARDENOIS, PATRICK;SEVRIN, MIREILLE;GEORGE, PASCAL |
发明人 |
DARGAZANLI, GIHAD;EVANNO, YANNICK;FROST, JONATHAN;LARDENOIS, PATRICK;SEVRIN, MIREILLE;GEORGE, PASCAL |
分类号 |
A61K31/00;A61K31/335;A61K31/357;A61K31/40;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61P9/00;A61P25/00;C07D319/06;C07D405/12;(IPC1-7):C07D319/06 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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