摘要 |
<p>The invention concerns human 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1) gene regulation. Specifically, the invention concerns the regulation of 1.3 kb 17HSD type 1 mRNA transcription. More specifically the invention concerns HSD17B1 promoter, enhancer and silencer regions and their use in the identification of trans-acting agents capable of up-regulating or down-regulating estrogen production.</p> |