发明名称 |
Protein which binds ATP and nucleic acid and which possesses putative helicase and ATPase properties |
摘要 |
Nucleic acid binding protein (I) with helicase activity, the mRNA of which (or its translation products) are strongly expressed in presence of leflunomide (II, i.e. 4-(N-(4-trifluoromethylphenyl)-5-methyl-isoxazole)) or compounds with similar activity is new. Also new are: (1) DNA (III) encoding (I), or parts of it, and sequences that hybridise under stringent conditions with (III); (2) vectors containing (III) or sequences antisense to (III) and (3) host cells containing (III) or the vectors. |
申请公布号 |
AU7407696(A) |
申请公布日期 |
1997.06.12 |
申请号 |
AU19960074076 |
申请日期 |
1996.12.02 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
BERND KIRSCHBAUM;STEFAN MULLNER;ROBERT BARTLETT |
分类号 |
C12N15/09;A61K38/00;C07K14/00;C07K14/47;C12N5/10;C12N9/90;C12N15/55;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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