| 摘要 |
<p>Sequence and binding information is provided for particularly advantageous specific binding members which bind human carcinoembryonic antigen (CEA) with a dissociation constant which is less than 1,0 x 10-8M, are substantially non-cross-reactive with human liver cells, bind to the A3-B3 extracellular domain of human carcinoembryonic antigen and/or bind to cell-associated human carcinoembryonic antigen preferentially over soluble human carcinoembryonic antigen. These are useful particularly in determination of CEA expression by cells such as tumour cells.</p> |
