发明名称 FLUOROPHENYL-TRIAZINE AND PYRIMIDINE DERIVATIVES AS COMPOUNDS ACTING ON THE CENTRAL NERVOUS SYSTEM
摘要 Novel fluorophenyl-triazine and pyrimidine derivatives of general formula (I), wherein R1 is an amino group, a 1-piperazinyl group or a 4-alkylpiperazin-1-yl group, where the alkyl group is a C1-4 chain, preferably methyl; each of R2, R3 and R4, which are the same or different, is a halogen atom, preferably a fluorine or chlorine atom; R5 is a hydrogen atom or a halogen atom, preferably a fluorine or chlorine atom; and Y is a nitrogen atom or a CH group, are disclosed. A method for preparing the compounds of formula (I) or physiologically acceptable salts thereof is also disclosed. Furthermore, pharmaceutical compositions containing a pharmaceutically acceptable carrier and at least one compound of general formula (I) or a physiologically acceptable salt thereof, are disclosed.
申请公布号 WO9720827(A1) 申请公布日期 1997.06.12
申请号 WO1996EP05593 申请日期 1996.12.04
申请人 LABORATORIOS DEL DR. ESTEVE, S.A.;TORRENS JOVER, ANTONI;FRIGOLA CONSTANSA, JORDI 发明人 TORRENS JOVER, ANTONI;FRIGOLA CONSTANSA, JORDI
分类号 C07D239/48;C07D253/075;(IPC1-7):C07D253/06;A61K31/495;A61K31/53 主分类号 C07D239/48
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